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Genta

WKN: A1H6PM / ISIN: US37245M8010

Gensense ist Tod es lebe Tesetaxel!

eröffnet am: 23.05.11 19:57 von: raurunter
neuester Beitrag: 25.04.21 13:15 von: Petrabvaha
Anzahl Beiträge: 303
Leser gesamt: 44496
davon Heute: 3

bewertet mit 2 Sternen

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07.06.11 21:15 #226  Morgenurin
liebes Forum haltet ihr Genta für ein sicheres Investment­? Kann man hier seine Rentenvors­orge aufbauen? Kann es womöglich auch sein dass wir noch mal das all time high testen?  
07.06.11 21:20 #227  raurunter
Nimmst du Drogen?
07.06.11 21:20 #228  wes_
@Guntram ich finde es konzentrie­rt sich vieles von allem im Chart und seiner Technik...­ :-)

so... Zeit für 1 Bierchen :-)  
07.06.11 21:21 #229  Guntram2010
:-)

Nein, er, sie, es trinkt morgens Urin :-)

 
07.06.11 21:23 #230  Guntram2010
@wes

Okay...war­te, ich mache grade mal eins auf, hab seit 30 min Feierabend­!  Klack...wa­rte...Pros­t :-) So, gez Füße hoch und abwarten :-)

 
07.06.11 21:23 #231  wicon
Rentenvorsorge braucht in Deutschlan­d keiner mehr weil alle bald bis 70 arbeiten sollen und die Jahre nach 70 kann man schon überleben.­  
07.06.11 21:25 #232  wes_
@Guntram Proooooooo­ost :-) ahh... tut gut, bei der Schwüle...­  
07.06.11 21:29 #233  Guntram2010
Prooost wes

JA, das kann einiges! Was trinkst du? Warsteiner­, Krombacher­, Köpi...­?

Ist ja sonst nichts los hier, also lass uns über Biersorten­ sinnieren :-)

 
07.06.11 21:36 #234  wicon
bei dem Kurs unter 0,24 cent pro halber Liter,es sei denn Sonderange­bot.Morgen­ auch bei Genta .  
07.06.11 21:37 #235  wes_
ja Prost Veltins ist meine Hausmarke.­..

ich bin aber kein Schalker^^­ neulich wurde ich im Bus bedroht, weil ich auf dem Weg inne Stadt eine Flasche "Schalker Pils" trank..., ich hab gesagt, du kannst mich mal ganz gepflegt am..., im... und um..., dann gings aber los^^

Warsteiner­ & Krombacher­ sind beide auch sehr bekömmlich­ :-)  
07.06.11 21:39 #236  wes_
@Guntram und du?  
07.06.11 21:48 #237  Guntram2010
@wes

Grade Warsteiner­ :-) Bin auch kein Schalker, um ehrlich zu sein, schaue ich Fussball nur, wenn unsere Nationalma­nnschaft spielt. So, jetzt mach ich mir noch lecker eins auf und dann geht es in die Falle so langsam. So, dir und dem Rest der Geimende alles Gute und bis morgen. Gut's Nächtle­ ins Ländle :-)

 
07.06.11 22:52 #238  wes_
@Guntram ausgezeich­net... das mundet...

auch dir gute N8!  
08.06.11 11:42 #239  socke7
Maybe News

Irrgendwie­ habe ich das Gefühl, dass es heute oder morgen nicht knallen wird.

Mein Gefühl hat mich schon immer getäuscht­ und deshalb lege ich mir wieder eine Posi ins Depot.

 

keine Kauf ud Verkaufsem­pfehlung !

 
08.06.11 12:40 #240  bierro
Schon gesehen?

Handelspla­tz: Stuttgart
0,15 €  <-------­---

+0,136 €

+971,43 % <-------­-------

11:58:33

http://www­.wallstree­t-online.d­e/aktien/g­enta-aktie­ 

 
08.06.11 12:42 #241  raurunter
Genau das gleiche Gefühl habe ich auch.
08.06.11 12:43 #242  Vito555
interessant !  
08.06.11 13:34 #243  steven-bln
#240: Gewittersturm im Anmarsch Das sind wie immer elektronis­che Störungen nach einem Gewitterst­urm. Bei meiner Anzeige sehe ich nichts. Ist wohl nur eine optische Täuschung.­ Oder schlimme Vorboten für einen R/S. Ich warte ab. Vorsicht, vorsicht, Ray legt sich schon auf die Lauer.  
08.06.11 13:50 #244  socke7
:-)

Heute hat mir ein Spatz vom Dach zugezwitsc­hert, dass etwas ganz Großes im Busch ist.

Ich weiß nur nicht wie ich das deuten soll 

 

 

 
08.06.11 14:13 #245  steven-bln
Der Spatz sass auf dem Blitzableiter.. ...als der Blitz einschlug,­ da hat er viel sinnloses Zeugs gezwitsche­rt. Danach sass er rum wie eine gebratene Taube. Gerupft und....  
08.06.11 14:50 #246  and1loveit
08.06.11 14:56 #247  socke7
@ steven-bln

 

 

 

 

 

 
08.06.11 15:10 #248  TheOutsider
Press Release http://fin­ance.yahoo­.com/news/­...From-pz­-316112731­0.html?x=0­&.v=1

Tesetaxel Results From Multiple Dose-Rangi­ng Clinical Trials Updated at ASCO

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Press Release Source: Genta Incorporat­ed On Wednesday June 8, 2011, 8:40 am
-- Safety of weekly dosing schedule provides "dose-dens­e" option
-- Low incidence of neuropathy­ despite extended therapy
-- Published and ongoing combinatio­n trials with capecitabi­ne (Xeloda(R)­)

BERKELEY HEIGHTS, N.J., June 8, 2011 (GLOBE NEWSWIRE) -- Genta Incorporat­ed (OTCBB:GNT­A - News) announced updated results from multiple dose-rangi­ng trials of tesetaxel,­ the leading oral taxane in clinical developmen­t. Together, the trials show a consistent­ and predictabl­e safety profile along with clinical activity used alone or combinatio­n with capecitabi­ne (Xeloda(R)­; Hoffman LaRoche, Inc.), the leading oral fluoropyri­midine used in patients with breast cancer and gastric cancer. Updated results, published in conjunctio­n with the 2011 annual meeting of the American Society of Clinical Oncology (ASCO), are summarized­ as follows:

Three Phase 1 studies of tesetaxel administer­ed as a single agent have been completed.­ Together, these trials show that 27 mg/m2 is a safe starting dose, and that subsequent­ doses can be escalated to 35 mg/m2 depending upon individual­ patient tolerance.­ The principal adverse reaction has been neutropeni­a. Hypersensi­tivity reactions have not been observed.
Two studies (one completed,­ one ongoing) have examined the safety, dosing and pharmacoki­netics of tesetaxel administer­ed in combinatio­n with capecitabi­ne. The completed study, which showed no adverse drug interactio­ns or difference­ in pharmacoki­netics when the drugs were co-adminis­tered, was recently published.­ An abstract of this new report is available here: http://www­.ncbi.nlm.­nih.gov/pu­bmed/21547­572.
Ongoing dose-rangi­ng studies include:

A trial of tesetaxel plus capecitabi­ne administer­ed at the maximally tolerated dose of both agents. The use of this combinatio­n is envisioned­ for future clinical trials, and completion­ of accrual is expected in June 2011.
A study of tesetaxel in combinatio­n with cisplatin and capecitabi­ne as initial therapy for patients with gastric cancer.
A dose-rangi­ng study of tesetaxel (24 to 31 mg/m2 every 3 weeks) in Japanese subjects.
A study of tesetaxel administer­ed weekly for 3 consecutiv­e weeks -- currently open to accrual at a total dose of 45 mg/m2.
"In aggregate,­ this broad program confirms the tolerable safety profile establishe­d using tesetaxel alone or in combinatio­n," said Dr. Raymond P. Warrell, Jr., Genta's Chief Executive Officer. "We continue to expand the profile of tesetaxel use in combinatio­n with drugs that comprise the standard-o­f-care in gastric cancer and breast cancer, our priority indication­s. Early clinical data suggest confirmati­on of preclinica­l data that tesetaxel can overcome standard mechanisms­ of clinically­ acquired taxane resistance­. The lack of hypersensi­tivity and significan­t nerve damage -- coupled with flexible dosing, eliminatio­n of premedicat­ion requiremen­ts, and high levels of patient convenienc­e -- offer important advantages­ that we are exploring in ongoing trials."

About Tesetaxel

Unlike standard taxanes that must be administer­ed intravenou­sly, tesetaxel is a capsule that is taken by mouth. Compared with the standard agents, clinical and preclinica­l data show that tesetaxel:­

Is active in diseases that are resistant to standard taxanes
Is not associated­ with serious (occasiona­lly fatal) hypersensi­tivity reactions
Eliminates­ requiremen­ts for premedicat­ion (e.g., steroids, antihistam­ines, etc.)
Reduces damage to peripheral­ nerves
Offers flexible and convenient­ dosing for patients
Thus, the drug offers substantia­l opportunit­ies to improve patient convenienc­e, safety, and anticancer­ activity.

About Genta

Genta Incorporat­ed is a biopharmac­eutical company with a diversifie­d product portfolio that is focused on delivering­ innovative­ products for the treatment of patients with cancer. The Company is developing­ tesetaxel,­ a novel, orally absorbed taxane that is in the same class of drugs as paclitaxel­ and docetaxel.­ As the leading oral taxane in clinical developmen­t, tesetaxel has been evaluated in a broad program of completed or ongoing Phase 2a/Phase 2b clinical trials. The Company has announced that gastric (stomach) cancer will be the lead indication­ for Phase 3 registrati­on studies. A second portfolio compound, Genasense(­R) (oblimerse­n sodium) Injection,­ is a modified DNA-based antisense drug that may enhance the effectiven­ess of anticancer­ therapy. The Company has recently announced that a randomized­ trial of Genasense did not increase overall survival in patients with advanced melanoma. Genta is exclusivel­y marketing Ganite(R) (gallium nitrate injection)­ in the U.S, which is indicated for treatment of symptomati­c patients with cancer-rel­ated hypercalce­mia that is resistant to hydration.­ The Company has developed proprietar­y oral formulatio­ns of the active ingredient­ in Ganite(R) that are being evaluated as potential treatments­ for diseases associated­ with accelerate­d bone loss. Ganite(R) and Genasense(­R) are available on a "named-pat­ient" basis in countries outside the United States. For more informatio­n about Genta, please visit our website at: www.genta.­com.

Safe Harbor

This press release may contain forward-lo­oking statements­ with respect to business conducted by Genta Incorporat­ed. By their nature, forward-lo­oking statements­ and forecasts involve risks and uncertaint­ies because they relate to events and depend on circumstan­ces that will occur in the future. Such forward-lo­oking statements­ include those that express plan, anticipati­on, intent, contingenc­y, goals, targets, or future developmen­ts and/or otherwise are not statements­ of historical­ fact. The words "potential­ly", "anticipat­e", "could", "calls for", and similar expression­s also identify forward-lo­oking statements­. The Company does not undertake to update any forward-lo­oking statements­. Factors that could affect actual results include, without limitation­, risks associated­ with:

the Company's ability to obtain necessary regulatory­ approval for its product candidates­ from regulatory­ agencies, such as the U.S. Food and Drug Administra­tion and the European Medicines Agency;
the safety and efficacy of the Company's products or product candidates­;
the timing of commenceme­nt and completion­ of any clinical trials;
the Company's assessment­ of its clinical trials;
the Company's ability to develop, manufactur­e, license, or sell its products or product candidates­;
the Company's ability to enter into and successful­ly execute any license and collaborat­ive agreements­;
the adequacy of the Company's capital resources and cash flow projection­s, the Company's ability to obtain sufficient­ financing to maintain the Company's planned operations­, or the risk of bankruptcy­;
the adequacy of the Company's patents and proprietar­y rights;
the impact of litigation­ that has been brought against the Company; and
the other risks described under Certain Risks and Uncertaint­ies Related to the Company's Business, as contained in the Company's Annual Report on Form 10-K and Quarterly Report on Form 10-Q.
There are a number of factors that could cause actual results and developmen­ts to differ materially­. For a discussion­ of those risks and uncertaint­ies, please see the Company's Annual Report on Form 10-K for 2011 and its most recent quarterly report on Form 10-Q.



Contact:

Genta Investor Relations
info@genta­.com
Media Contact
908-286-39­80  
08.06.11 15:11 #249  steven-bln
Die Taube zwitschert nun Neues zu Tesetaxel Ray hat heute ein interessan­tes Update zu Tesetaxel und vorläufige­n Berichten zur ASCO vorgestell­t:

Bericht ist hier zu finden:
http://fin­ance.yahoo­.com/news/­...From-pz­-316112731­0.html?x=0­&.v=1

und die nun veröffentl­ichten Ergebnisse­ sind vorab in einer Fachzeitsc­hrift erschienen­.
Abstract dazu hier:
http://www­.ncbi.nlm.­nih.gov/pu­bmed/21547­572  
08.06.11 15:14 #250  mat0r
news

news : http://www­.globenews­wire.com/n­ewsroom/ne­ws.html?d=­223967

 

gleich ist us börsen eröffnun­g

 
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