Achieve Life Sciences Inc
WKN: A2QAR3 / ISIN: US0044685008Achieve Life Sciences nach Reverse Split
| eröffnet am: | 25.05.18 17:22 von: | bozkurt7 |
| neuester Beitrag: | 04.02.26 11:33 von: | Highländer49 |
| Anzahl Beiträge: | 953 | |
| Leser gesamt: | 316085 | |
| davon Heute: | 232 | |
bewertet mit 3 Sternen |
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02.04.19 13:51
#578
martin30sm
Ich bin gespannt ob mein durchschnittlicher
Einkaufskurs von 7,82 Dollar nochmals erreicht wird?....
02.04.19 14:13
#579
action72
Glaubt ihr
Vorher gibts noch ne Kapitalerhöhungen
Wegen Distribution oder so?
Wegen Distribution oder so?
03.04.19 13:03
#580
Dagobert_0815
Wichtige Präsentation am 08.04.2019
https://ih.advfn.com/stock-market/NASDAQ/...-present-at-hc-wainwright
03.04.19 14:00
#581
brauchmehrkohle
Ich denke ich nächster Zeit
Wird hier neu bewertet! Und zwar deutlich höher wie jetzt
04.04.19 19:41
#582
Blutegel
Über 3,50 $ bei den Amis heute ...
... und der Chart sieht weiterhin sehr gut aus.
https://www.ariva.de/chart/images/...8~A1~b40~H0~w940x420~Uquarter~W1
Bleibe weiter dabei und freue mich auf mehr gute Nachrichten von der Butze! :-)
https://www.ariva.de/chart/images/...8~A1~b40~H0~w940x420~Uquarter~W1
Bleibe weiter dabei und freue mich auf mehr gute Nachrichten von der Butze! :-)
05.04.19 11:47
#586
brauchmehrkohle
Glaub ich gar nicht das es Sonnabend dauert
Kurs sieht ganz schön stark nach Ausbruch aus. Und wenn noch positive news kommen.... extreme unterbewertet wenn es zur Zulassung kommt
05.04.19 16:35
#588
Dagobert_0815
...heute bereits knapp 8% +
Montag nach der Präsentation kommt der Nachschlag...
m.M.
m.M.
05.04.19 19:37
#589
Advamillionär
Das riecht hier...
...ganz gewaltig nach einem neuerlichen Ausbruch nach oben.
Gruß vom
Advamillionär
Gruß vom
Advamillionär
22.04.19 20:53
#590
Dagobert_0815
Läuft...
Wieder 8% plus, der Goldesel funktioniert weiterhin. Kurzfristig wird die 4 $ Marke geknackt. Wie immer meine Meinung
24.04.19 13:27
#591
martin30sm
News
Achieve Life Sciences Announces Last Subject, Last Visit Completed in Phase 2b ORCA-1 Trial of Cytisinicline for Smoking Cessation
Topline data from ORCA-1 trial expected in the Second Quarter of 2019
SEATTLE and VANCOUVER, British Columbia, April 24, 2019 /PRNewswire/ -- Achieve Life Sciences, Inc. (Nasdaq: ACHV), a clinical-stage pharmaceutical company committed to the global development and commercialization of cytisinicline for smoking cessation, today announced that the last study visit for the last subject enrolled in the ORCA-1 trial occurred on April 23, 2019. ORCA-1 topline efficacy and safety data are expected to be announced by the end of the second quarter.
ORCA-1 is the first in Achieve's ORCA (Ongoing Research of Cytisinicline for Addiction) Program, which aims to evaluate the effectiveness of cytisinicline for smoking cessation and potentially other addiction indications. ORCA-1 was initiated in October 2018 and enrolled 254 smokers at eight centers across the United States. Importantly, the trial's Data Safety Monitoring Committee met recently to conduct its final safety review and concluded there are no safety concerns for subjects or study conduct issues, and the trial should continue for completion.
Dr. Cindy Jacobs, Chief Medical Officer at Achieve commented, "Completing this trial represents a significant milestone in the cytisinicline development program and we continue to be impressed by the efficient conduct of our investigators and the commitment of the subjects who, like millions of people, are combatting nicotine addiction."
Additional information on cytisinicline and the ORCA program can be found at www.achievelifesciences.com and www.orcaprogram.com.
About Cytisinicline
Tobacco use is currently the leading cause of preventable death and is responsible for nearly seven million deaths annually worldwide1. It is estimated that 28.7% of cancer deaths in the U.S. are attributable to cigarette smoking2. Achieve's focus is to address the global smoking health epidemic through the development and commercialization of cytisinicline.
Cytisinicline is a plant-based alkaloid with a high binding affinity to the nicotinic acetylcholine receptor. It is believed to aid in smoking cessation by interacting with nicotine receptors in the brain by reducing the severity of nicotine withdrawal symptoms and by reducing the reward and satisfaction associated with smoking.
As an approved, branded product in Central and Eastern Europe for more than two decades, it is estimated that over 20 million people have used cytisinicline to help combat nicotine addiction.
About ORCA-1
The Phase 2b ORCA-1 trial is evaluating a 25-day treatment course of 1.5 mg or 3.0 mg doses of cytisinicline using either a declining titration schedule or three times daily dosing. The trial is randomized and blinded to compare the effectiveness of the cytisinicline doses and schedules to respective placebo groups. The primary efficacy endpoint is the overall reduction in the number of cigarettes smoked during the treatment period, with secondary analyses being conducted on smoking cessation rates, safety, and compliance. Smokers who are participating in the trial receive standardized behavioral support.
Forward Looking Statements
This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995, including, but not limited to, statements regarding the planned cytisinicline clinical development activities, the timing of clinical development activities related to cytisinicline, the potential market size for cytisinicline and the potential benefits of cytisinicline. All statements other than statements of historical fact are statements that could be deemed forward-looking statements. Achieve may not actually achieve its plans or product development goals in a timely manner, if at all, or otherwise carry out its intentions or meet its expectations or projections disclosed in these forward-looking statements. These statements are based on management's current expectations and beliefs and are subject to a number of risks, uncertainties and assumptions that could cause actual results to differ materially from those described in the forward-looking statements, including, among others, the risk that cytisinicline may not demonstrate the hypothesized or expected benefits; the risk that Achieve may not be able to obtain additional financing to fund the development of cytisinicline; the risk that cytisinicline will not receive regulatory approval or be successfully commercialized; the risk that new developments in the smoking cessation landscape require changes in business strategy or clinical development plans; the risk that Achieve's intellectual property may not be adequately protected; general business and economic conditions; and the other factors described in the risk factors set forth in Achieve's filings with the Securities and Exchange Commission from time to time, including Achieve's Annual Reports on Form 10-K and Quarterly Reports on Form 10-Q. Achieve undertakes no obligation to update the forward-looking statements contained herein or to reflect events or circumstances occurring after the date hereof, other than as may be required by applicable law.
Achieve Contact
Jason Wong
jwong@bplifescience.com
(415) 375-3340 ext. 4
"ORCA is a trademark of Achieve Life Sciences, Inc."
1World Health Organization. WHO Report on the Global Tobacco Epidemic, 2017. Geneva: World Health Organization, 2017
2Annals of Epidemiology , Volume 25 , Issue 3 , 179 - 182.e1
SOURCE Achieve Life Sciences, Inc.
Topline data from ORCA-1 trial expected in the Second Quarter of 2019
SEATTLE and VANCOUVER, British Columbia, April 24, 2019 /PRNewswire/ -- Achieve Life Sciences, Inc. (Nasdaq: ACHV), a clinical-stage pharmaceutical company committed to the global development and commercialization of cytisinicline for smoking cessation, today announced that the last study visit for the last subject enrolled in the ORCA-1 trial occurred on April 23, 2019. ORCA-1 topline efficacy and safety data are expected to be announced by the end of the second quarter.
ORCA-1 is the first in Achieve's ORCA (Ongoing Research of Cytisinicline for Addiction) Program, which aims to evaluate the effectiveness of cytisinicline for smoking cessation and potentially other addiction indications. ORCA-1 was initiated in October 2018 and enrolled 254 smokers at eight centers across the United States. Importantly, the trial's Data Safety Monitoring Committee met recently to conduct its final safety review and concluded there are no safety concerns for subjects or study conduct issues, and the trial should continue for completion.
Dr. Cindy Jacobs, Chief Medical Officer at Achieve commented, "Completing this trial represents a significant milestone in the cytisinicline development program and we continue to be impressed by the efficient conduct of our investigators and the commitment of the subjects who, like millions of people, are combatting nicotine addiction."
Additional information on cytisinicline and the ORCA program can be found at www.achievelifesciences.com and www.orcaprogram.com.
About Cytisinicline
Tobacco use is currently the leading cause of preventable death and is responsible for nearly seven million deaths annually worldwide1. It is estimated that 28.7% of cancer deaths in the U.S. are attributable to cigarette smoking2. Achieve's focus is to address the global smoking health epidemic through the development and commercialization of cytisinicline.
Cytisinicline is a plant-based alkaloid with a high binding affinity to the nicotinic acetylcholine receptor. It is believed to aid in smoking cessation by interacting with nicotine receptors in the brain by reducing the severity of nicotine withdrawal symptoms and by reducing the reward and satisfaction associated with smoking.
As an approved, branded product in Central and Eastern Europe for more than two decades, it is estimated that over 20 million people have used cytisinicline to help combat nicotine addiction.
About ORCA-1
The Phase 2b ORCA-1 trial is evaluating a 25-day treatment course of 1.5 mg or 3.0 mg doses of cytisinicline using either a declining titration schedule or three times daily dosing. The trial is randomized and blinded to compare the effectiveness of the cytisinicline doses and schedules to respective placebo groups. The primary efficacy endpoint is the overall reduction in the number of cigarettes smoked during the treatment period, with secondary analyses being conducted on smoking cessation rates, safety, and compliance. Smokers who are participating in the trial receive standardized behavioral support.
Forward Looking Statements
This press release contains forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995, including, but not limited to, statements regarding the planned cytisinicline clinical development activities, the timing of clinical development activities related to cytisinicline, the potential market size for cytisinicline and the potential benefits of cytisinicline. All statements other than statements of historical fact are statements that could be deemed forward-looking statements. Achieve may not actually achieve its plans or product development goals in a timely manner, if at all, or otherwise carry out its intentions or meet its expectations or projections disclosed in these forward-looking statements. These statements are based on management's current expectations and beliefs and are subject to a number of risks, uncertainties and assumptions that could cause actual results to differ materially from those described in the forward-looking statements, including, among others, the risk that cytisinicline may not demonstrate the hypothesized or expected benefits; the risk that Achieve may not be able to obtain additional financing to fund the development of cytisinicline; the risk that cytisinicline will not receive regulatory approval or be successfully commercialized; the risk that new developments in the smoking cessation landscape require changes in business strategy or clinical development plans; the risk that Achieve's intellectual property may not be adequately protected; general business and economic conditions; and the other factors described in the risk factors set forth in Achieve's filings with the Securities and Exchange Commission from time to time, including Achieve's Annual Reports on Form 10-K and Quarterly Reports on Form 10-Q. Achieve undertakes no obligation to update the forward-looking statements contained herein or to reflect events or circumstances occurring after the date hereof, other than as may be required by applicable law.
Achieve Contact
Jason Wong
jwong@bplifescience.com
(415) 375-3340 ext. 4
"ORCA is a trademark of Achieve Life Sciences, Inc."
1World Health Organization. WHO Report on the Global Tobacco Epidemic, 2017. Geneva: World Health Organization, 2017
2Annals of Epidemiology , Volume 25 , Issue 3 , 179 - 182.e1
SOURCE Achieve Life Sciences, Inc.
24.04.19 13:33
#592
brauchmehrkohle
Hier gibt es nur noch eine Richtung
Die Bewertung ist in meinen Augen Anpassungsfähig
24.04.19 14:57
#595
Dagobert_0815
M.E. sind die News bereits seit
gestern durch die US Amerikaner eingepreist, ich erwarte kurzfristig keine signifikanten Steigerungen.
Long natürlich weiterhin der Knaller.
Wie immer m.M.
Long natürlich weiterhin der Knaller.
Wie immer m.M.
24.04.19 17:45
#596
brauchmehrkohle
volumen steigt!
wann wohl der Deckel fliegt 10.... 20... Euro.... Übernahme?? die Bewertung ist ein Witz und ich glaube es geben nicht viele ihre Aktien her. Tenbaggeralarm
26.04.19 20:52
#597
Advamillionär
Das hier schreit förmlich...
...nach einem Ausbruch nach oben!
Gruß vom
Advamillionär
Gruß vom
Advamillionär
29.04.19 10:36
#598
brauchmehrkohle
Der schrei wird lauter
Es gibt nur so wenig Aktien und die meisten werden wohl behalten bei der mk. Für mich völlig unterbewertet könnte sich locker verzehnfachen
29.04.19 13:46
#599
Neonblack667
und ich bin auch endlich im Plus
Hab mir zwar geschworen, dass ich, wenn das dass nächste mal der Fall sein wird, verkaufe und nach dem üblichen Crash wieder unten einsteige aber ich glaube fast, dass es diesmal keinen massiven Rücksetzer mehr gibt...
29.04.19 18:54
#600
Advamillionär
Wohl nur dann, wenn...
...es nochmal richtig hochschießen sollte (wovon ich bald ausgehe), also mehr als 50 % Tagesgewinn. Dann wird es sicherlich wieder die üblichen Gewinnmitnahmen geben. Aber derzeit geht es langsam und kontinuierlich bergauf, die Gefahr eines größeren Rücksetzers stufe ich daher aktuell als sehr niedrig ein.
Gruß vom
Advamillionär
Gruß vom
Advamillionär